New York City College of Technology - Biological Sciences - Faculty

Liana Tsenova

Office:
» Pearl 313 (P-313)

Phone:
» 718.260.5960

Liana Tsenova

Dr. Tsenova is an Assistant Professor at City Tech since 2008. Dr. Tsenova received her M.D. degree from the Medical Academy of Sofia, Bulgaria. She then obtained her specialty in Microbiology and Immunology from the same institute. In 1993 Dr. Tsenova came to the Rockefeller University, NY with an international John Fogarty fellowship. Later on she continued her postdoctoral training there, at the Laboratory of Cellular Physiology and Immunology. Currently she works also as an adjunct professor at the PHRI Center at UMDNJ, Newark, NJ. Her major research interests are in host-pathogen interactions in tuberculosis, role of cytokines in the immune response, design of immunomodulatory therapy, and evaluation of new anti TB candidate vaccines, using experimental animal models. At City Tech Dr. Tsenova serves at the Coordination of Student Research Committee and works as a mentor for undergraduate students. She is interested in collaborative interdisciplinary projects, combining microbiology and infectious diseases with mathematics to address unresolved epidemiologic, ecologic and healthcare problems. She has authored more than 50 publications in peer-reviewed scientific journals and chapters.

At City Tech Dr. Tsenova teaches Microbiology and General Biology I. She is currently the Interim Program Coordinator of the BS Degree Program in Radiological Science at the Department of Radiologic Technology and Medical Imaging.

Recent Publications:

Subbian S., L. Tsenova, P. O’Brien, G. Yang, N. Lynn Hart, S. Parsons, B. Peixoto, D. Fallows and G. Kaplan. Spontaneous Latency in a Rabbit Model of Pulmonary Tuberculosis. Am J Pathol. Am J Pathol. 2012 Sep 5. http://www.journals.elsevierhealth.com/periodicals/ajpa/article/S0002-9440(12)00586-X/abstract
Subbian S., L. Tsenova, G Yang, P O’Brien, S Parsons, B Peixoto, L Taylor, D Fallows and G Kaplan. Chronic Pulmonary Cavitary Tuberculosis in Rabbits: a Failed Host Immune Response. Open Biology. 2011, 1: 110016.
http://rsob.royalsocietypublishing.org/content/1/4/110016.full.pdf+html
Ghosh-Dastidar U. and L. Tsenova. Bio-Math Mapping: Water Quality Analysis of Hudson River and Gowanus Canal, A SENCER-based Summer Project. Science Education and Civic Engagement : An International Journal. 4:1 winter 2012
http://seceij.net/seceij/winter12/bio-math_mappin.html
Subbian S., L. Tsenova, P. O’Brien, G. Yang, M. Koo, D. Fallows, V. Dartois, G. Muller and G. Kaplan. Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs. PLoS Pathog. 2011 Sep;7(9):e1002262. Epub 2011 Sep 15. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174258/
Subbian S., L. Tsenova, P. O’Brien, G. Yang, M. Koo, B. Peixoto, D. Fallows, J. Zeldis, G. Muller and G. Kaplan. PDE4 inhibition combined with INH treatment of rabbits with pulmonary tuberculosis reduces macrophage activation and lung pathology. Am J Pathol. 2011 Jul;179(1):289-301. http://www.ncbi.nlm.nih.gov/pubmed/21703411
Singhal. A, Aliouat E, Hervé M, Mathys V, Kiass M, Creusy C, Delaire B, Tsenova L, Bertout L, Camacho L, Foo D, Tay H.C, Yee S. J, Boukhouchi W, Romano M, Mathema B, Dartois V, Kaplan G, Bifani P. Experimental tuberculosis in the Wistar rat: A model for protective immunity and control of infection, PLoS One. 2011 Apr 12;6(4):e18632. http://www.ncbi.nlm.nih.gov/pubmed/21533270
Koo M., C. Manca, G. Yang, P. O’Brien, N. Sung, L. Tsenova, S. Subbian, D. Fallows, G. Muller, S. Ehrt and G. Kaplan. Phosphodiesterase 4 Inhibition Reduces Innate Immunity and Improves Clearance of Mycobacterium tuberculosis in the Lungs of Infected Mice. PLoS ONE, Feb 2011:6(2) http://www.ncbi.nlm.nih.gov/pubmed/21364878
Kana BD, G.L. Abrahams, N. Sung, D.F. Warner, B.G. Gordhan, E.E. Machowski, L. Tsenova, J.C. Sacchettini, N. G. Stoker, G. Kaplan and V. Mizrahi. Role of the DinB Homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis. J Bacteriol. 2010 Apr;192(8):2220-7. Epub 2010 Feb 5. http://www.ncbi.nlm.nih.gov/pubmed/20139184
Kim MJ, Wainwright HC, Locketz M, Bekker LG, Walther GB, Dittrich C, Visser A, Wang W, Hsu FF, Wiehart U, Tsenova L, Kaplan G, Russell DG. Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism. EMBO Mol Med. 2010 Jul;2(7):258-74. http://www.ncbi.nlm.nih.gov/pubmed/20597103

Peer-Reviewed Scholarly Books (Chapters):

G. Kaplan and L. Tsenova. Chapter 7: Pulmonary tuberculosis in the rabbit, in: A Colour Atlas of Comparative Pulmonary Tuberculosis Histopathology. Ed. F. J. Leong, V. Dartois & T. Dick. CRC Press, Taylor &Francis Group 2010.
J. L. Flynn, L. Tsenova, A. Izzo, G. Kaplan. Experimental Animal Models of Tuberculosis. In: SHE Kaufmann, E. Rubin, W. Britton and P. van Helden eds. Handbook of Tuberculosis: Immunology and Cell Biology. WILEY-VCH Verlag GmbH & Co. KgaA, Weinheim, 2008. http://www.wiley-vch.de/books/sample/3527318879_ftoc.pdf

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