Eugenia G. Giannopoulou

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Eugenia G. Giannopoulou


    Ph.D., Computer Science - Bioinformatics, 2009
  • Department of Computer Science and Technology, University of Peloponnese
  • Biomedical Research Foundation of the Academy of Athens
  • Dissertation: "Integration and Visualization of Proteomics Data"
    BSc, Computer Science, 2004
  • Department of Computer Science
  • Athens University of Economics and Business

Courses Taught at City Tech:

  • BIO 3352: Bioinformatics II
  • BIO 3354: Computational Genomics

Research Interests:

  • Bioinformatics/Computational Biology
  • Analysis of high-throughput sequencing data
  • Methlyation in Cancer
  • Epigenomics landascape of rheumatic diseases
  • Regulatory Network Inference
  • Information Visualization in genomics and proteomics
  • Ontologies in biology
  • Data Mining

Previous Appointments:

    Assistant Computational Genomics Scientist (2013 - 2014)
  • Department of Physiology and Biophysics, Applied Bioinformatics Core
  • Weill Cornell Medical College
    Postdoctoral associate (2009 - 2013)
  • Institute for Computational Biomedicine
  • Weill Cornell Medical College (Elemento lab)
    Research Associate (2005 - 2009)
  • Virtual Reality & Human-Computer Interaction Lab
  • University of Peloponnese, Greece
    Research Associate (2005 - 2009)
  • Virtual Reality & Human-Computer Interaction Lab
  • Biomedical Research Foundation, Academy of Athens (BRFAA), Greece
    Research Associate (2005)
  • Data and Web Mining Team (DB-NET)
  • Athens University of Economics and Business, Greece

Representative Publications:

  • Popovic R, Martinez-Garcia E, Giannopoulou EG, Zhang Q, Zhang Q, Ezponda T, Shah MY, Zheng Y, Will CM, Small EC et al: Histone Methyltransferase MMSET/NSD2 Alters EZH2 Binding and Reprograms the Myeloma Epigenome Through Global and Focal Changes in H3K36 and H3K27 Methylation. Plos Genetics 2014, Accepted, In Press.
  • Donlin LT, Jayatilleke A, Giannopoulou EG, Kalliolias GD, Ivashkiv LB: Modulation of TNF-Induced Macrophage Polarization by Synovial Fibroblasts. The Journal of Immunology 2014, Accepted, In Press
  • Walker S, Liu S, Xiang M, Nicolais M, Hatzi K, Giannopoulou EG, Elemento O, Cerchietti L, Melnick A, Frank D: The transcriptional modulator BCL6 as a molecular target for breast cancer therapy. Oncogene 2014.
  • Chang C-Y, Pasolli HA, Giannopoulou EG, Guasch G, Gronostajski RM, Elemento O, Fuchs E: NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. Nature 2013.
  • Giannopoulou EG, Elemento O: Inferring chromatin-bound protein complexes from genome-wide binding assays. Genome Research 2013, 23(8):1295-1306.
  • Qiao Y, Giannopoulou EG, Chan CH, Park S-h, Gong S, Chen J, Hu X, Elemento O, Ivashkiv LB: Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and Toll-like receptor signaling. Immunity 2013, 39(3):454-469.
  • Qiao Y, Giannopoulou EG, Elemento O, Ivashkiv L: Priming of regulatory DNA elements activates inflammatory cytokine genes synergistically with TLR signaling to increase transcription (P1230). The Journal of Immunology 2013, 190:138.113.
  • Lin P-C, Giannopoulou EG, Park K, Mosquera JM, Sboner A, Tewari AK, Garraway LA, Beltran H, Rubin MA, Elemento O: Epigenomic alterations in localized and advanced prostate cancer. Neoplasia 2013, 15(4):373-IN375.
  • Lin P-C, Chiu Y-L, Banerjee S, Park K, Mosquera JM, Giannopoulou EG, Alves P, Tewari AK, Gerstein MB, Beltran H: Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression. Cancer research 2013, 73(3):1232-1244.
  • Hatzi K, Jiang Y, Huang C, Garrett-Bakelman F, Gearhart MD, Giannopoulou EG, Zumbo P, Kirouac K, Bhaskara S, Polo JM: A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters. Cell reports 2013, 4(3):578-588.
  • Delehouzé C, Godl K, Loaëc N, Bruyère C, Desban N, Oumata N, Galons H, Roumeliotis T, Giannopoulou EG, Grenet J: CDK/CK1 inhibitors roscovitine and CR8 downregulate amplified MYCN in neuroblastoma cells. Oncogene 2013.
  • Roumeliotis TI, Halabalaki M, Alexi X, Ankrett D, Giannopoulou EG, Skaltsounis A-L, Sayan BS, Alexis MN, Townsend PA, Garbis SD: Pharmacoproteomic study of the natural product Ebenfuran III in DU-145 prostate cancer cells: The quantitative and temporal interrogation of chemically induced cell death at the protein level. Journal of proteome research 2013, 12(4):1591-1603.
  • Giannopoulou EG, Lepouras G, Manolakos ES: Visualizing Meta-Features in Proteomic Maps. BMC Bioinformatics 2011, 12(1):308.
  • Giannopoulou EG, Elemento O: An integrated ChIP-seq analysis platform with customizable workflows. BMC Bioinformatics 2011, 12(1):277.
  • Giannopoulou EG, Garbis SD, Vlahou A, Kossida S, Lepouras G, Manolakos ES: Proteomic feature maps: a new visualization approach in proteomics analysis. Journal of biomedical informatics 2009, 42(4):644-653.
  • Giannopoulou EG, Kossida S: Data Mining Applications in the Post-Genomic Era: Data Mining in Medical and Biological Research; 2008.
  • Garbis SD, Tyritzis SI, Roumeliotis T, Zerefos P, Giannopoulou EG, Vlahou A, Kossida S, Diaz J, Vourekas S, Tamvakopoulos C: Search for potential markers for prostate cancer diagnosis, prognosis and treatment in clinical tissue specimens using amine-specific isobaric tagging (iTRAQ) with two-dimensional liquid chromatography and tandem mass spectrometry. The Journal of Proteome Research 2008, 7(8):3146-3158.
  • Katifori A, Halatsis C, Lepouras G, Vassilakis C, Giannopoulou E: Ontology visualization methods–a survey. ACM Computing Surveys (CSUR) 2007, 39(4):10. ACM Digital Library
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